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    Institutional Review Board (IRB)

    The Maryland Department of Health (MDH) Institutional Review Board (IRB) is responsible for reviewing and approving all proposed research projects involving human subjects covered by 45 Code of Federal Regulations (CFR) Part 46 as well as, 21 CFR 50 and 56, occurring in any MDH facility or involving any MDH program.  The primary purpose of the IRB is to protect the rights and dignity of individuals who volunteer to participate in human subject research.  

    The MDH IRB shall review all human subject research projects that are: funded with federal, State, or other funds available from or through MDH; the human subjects are patients or clients of MDH; the data sought by the investigator is data held or compiled by or for MDH; and the investigator is an employee of MDH or a student in a residency program at MDH, if the employee or student  is conducting the research as a function of his employment or training.  The IRB is charged with the responsibility of determining if a project qualifies as being exempt from IRB review requirements.​

    The MDH IRB has an approved Federal-wide Assurance (FWA0002813​), approved through 03/27/2023​​

    IRB Proposal Application Process 

    Complete IRB Application

    • Research involving any MDH unit or facility must be signed off by the Director or Administrator of the unit or facility.

    • The Director's signature should appear on the line designated for the 'MDH program administrator' on IRB form 1 (MDH 2124, 'Attachment 3').

    Mental Health Institutions Research Approval Committee

    • Any proposal that involves research in one of these facilities must be approved by that facility's review board. (See Attachment 1).

    IRB Review 

    • The deadline for proposals to be included for each meeting's agenda is 10 calendar days prior to the meeting date.

    When your proposal has been scheduled for review, you will be informed of the date and approximate time of the review. Although it is not required that the principal investigator attends the IRB meeting, his or her doing so can facilitate the process should the Board members have questions regarding the protocol to be followed to carry out the proposal.

    For more information or questions preparing your proposal for submission, please feel free to contact:

    IRB Contact

    Maryland Department of Health
    Office of the Inspector General
    IRB Administrator
    201 W. Preston Street
    Baltimore, MD 21201
    410-767-8949 office
    410-333-7194 fax​