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Maryland Department of Health
Genetics
Genetics
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Sickle Cell Disease
What is Sickle Cell Disease?
What is Sickle Cell Trait?
How can SCT impact a person’s health?
What do I need to know about SCT and sports?
How is Sickle Cell Trait (SCT) Inherited?
What does the Maryland Department of Health’s Sickle Cell Disease Follow-Up Program do?
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Office for Genetics and People with Special Health Care Needs
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Indications for Genetic Counseling
and/or Education In Obstetric Practice
Recurrent pregnancy loss/stillbirth.
Couples of "advanced age" (females over 35 and/or males over 55) who are considering pregnancy or expecting.
Primary amenorrhea, aspermia, infertility or abnormal sexual development.
Previous history or family history of children with multiple malformations and/or mental retardation.
Known familial chromosomal abnormality.
Common birth defects (cleft lip/palate, neural tube defects, multiple vertebral anomalies, congenital heart disease, clubfoot, dislocated hips, etc.).
Elevated maternal serum alpha fetoprotein.
Couples in which the spouses are related.
Couples with an ethnic background suggesting a high risk for any disorder (Jewish couples for Tay-Sachs screening, Black/Mediterranean couples with positive screens for a sickle hemoglobinopathy or thalessemia, etc.).
Woman exposed to potential teratogens - radiation; chemicals; certain medications (anticonvulsants, anticoagulants, antimetabolites, thyroid antagonists, steroids, etc.); recreational drugs (including alcohol); certain viral agents; very high fevers, etc.
Women considering pregnancy who themselves have a hereditary disorder even though treated and clinically normal (PKU, homocystinuria, etc.).
Families with known hereditary conditions and/or questions about recurrence risks.
History of any disease "running in the family," especially hearing loss; blindness; neurodegenerative disorders; short stature; premature heart disease; immune deficiency; abnormalities of the hair, skin or bones; or mental retardation.
Couples with questions about prenatal diagnosis for any disorder.
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